The 8 Best Cat Pee, Odor, and Stain Removal Products of 2021

Best Overall: ANGRY ORANGE Pet Odor Eliminator Spray

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Angry Orange's enzyme-based cleaner is a longtime staple of many cat owners, and its new ready-to-use spray formula is a welcome change (previously you had to mix it from a concentrate, an option that’s still available and more cost-effective). The enzymes help to lift the odors, not simply cover them up, while the main ingredient, orange oil, leaves behind a pleasant citrus scent. To treat a stain—fresh or dried—blot the area first, then spray liberally, and let sit for 10 to 15 minutes before wiping up any excess liquid. The spray is safe to use on carpets, tiles, wood floors, litter boxes, garbage cans, pillows, mattresses, car interiors, and more.

Best Commercial-Grade: BUBBA'S ROWDY FRIENDS Super Strength Commercial Enzyme Cleaner - Pet Odor Eliminator

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Bubba’s uses dormant enzymes, which according to the company’s website, are more powerful as they don’t start working until they come into contact with a stain—and keep on working from there to digest organic bacteria, i.e., cat pee and feces, whereas an “active” enzyme doesn’t have the same staying power. The cleaner, made in Florida, is approved by the Carpet and Rug Institute, and can also be used on hardwood floors and to pretreat laundry, if say, kitty had an accident on your bedsheets. It leaves behind a minty scent that reviewers say is refreshing without being overly pungent. The only complaint is that it’s not available in a spray bottle, so you’ll have to pour it into your own.

Best Natural: Sunny & Honey Pet Stain & Odor Miracle - Enzyme Cleaner

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If protecting your pet and the earth is as important to you as your decor, this Leaping Bunny Certified  bio-enzymatic formula is made for you. It’s biodegradable and non-toxic, and scented with essential oils, and the company donates 10 percent of all its profits to rescue groups and no-kill animal shelters. It’s effective on all types of pet stains, even drool. It can be used on carpets, rugs, hardwood floors, laminate, tile, concrete, furniture, mattresses, leather, litter box, car upholstery, and even outdoors on your deck or patio. Reviewers report that it’s effective at eliminating stains and odors though some found it’s minty scent to be overpowering.

Best Spray: Rocco & Roxie Supply Co Professional Strength Pet Stain & Odor Eliminator

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This spray uses a combination of enzymes and bacteria for an effective one-two punch that fully removes urine and its lingering scent. To make your bottle of Rocco & Roxie spray go further, the company recommends treating the area with water first to dilute the urine, then liberally applying the product. It’s approved for use on carpets and reviewers say they’ve had good results using it on wood, tile, upholstery, leather, and more. The product has a strong minty scent, which some find to be too strong. Rocco & Roxie is based in the United States and the company also makes treats and toys.

Best Scent: The Spruce Stain and Odor Remover in Fresh

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The best cat pee stain removers erase cat pee stains and odors and leave behind a pleasant scent, and this from The Spruce's Stain and Odor Remover delivers on both counts.

As for the first part, this spray uses a powerful plant-derived enzyme formula that’s free of chlorine and dyes; as for the scent, it’s a synthetic-free blend of neroli, apple, and orchid that’s described as crisp and bright. To use, shake first, then spray on the area, letting it soak in for up to 15 minutes before brushing to lift the odor, then wipe clean. This set comes with a 2-ounce spray bottle that’s perfect for traveling.

Best for Carpets: Nature's Miracle Deep Cleaning Pet Stain and Odor Carpet Shampoo

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This deep cleaning carpet shampoo from well-known brand Nature’s Miracle can be safely used to spot treat stains or for all over cleaning with a machine. When using, it’s important to not only treat your rug, but also any rug pads and the floor underneath in case the pee soaked through. Some complain that this product has a chemical-like smell; the brand says that’s evidence that the product’s enzymes are at work breaking down the organic waste and that once that process is complete, the scent will fade. The shampoo also removes allergens and can safely be used to pre-treat laundry.

Best for Furniture: Arm & Hammer plus Oxi Clean Pet Stain & Odor Eliminator for Carpet

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If your cat keeps peeing on your favorite chair, cleaning up the stain with this cleaner should do the trick of preventing them from returning to it again while removing any lingering odor. It uses Arm & Hammer baking soda to neutralize odors instantly and Oxi Clean enzymatic cleaner to remove any visible stains and odor left behind. It comes in an easy-to-use spray bottle and can be used on carpets or upholstery. It’s also one of the more affordable options available and in addition to pet stains, you can use it to treat grease, oil, and other common household stains.