The 8 Best Probiotics for Dogs in 2022

The Purina Fortiflora Canine Nutritional Supplement is our top choice for dogs

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Best Probiotics for Dogs

The Spruce / Sabrina Jiang

Reviewed & Approved

Purina Fortiflora Canine Nutritional Supplement is our top choice, thanks to its ease of use. We also like PetVitalityPro Probiotic Chews.

When it comes to canine wellness, your dog may be missing a crucial element: good bacteria. A healthy gut contains good bacteria that breaks down food and can help with digestion. But if the gut becomes unbalanced, bad bacteria may overtake the healthy microorganisms that should be in your dog’s stomach and intestines. A probiotic can help restore and maintain this balance of good and bad bacteria. Probiotics for dogs come in many forms, and some brands even claim to address other canine health concerns, like joint pain and allergies.

We researched the market to find the best probiotics for dogs.

Our Top Picks

Best Overall: Purina Fortiflora Canine Nutritional Supplement

Purina Fortiflora Canine Nutritional Supplement Box

Courtesy of Amazon

Purina Fortiflora Canine Nutritional Supplement comes in pre-measured packets and is one of the easiest and most popular ways to ensure that your dog is getting a daily dose of probiotics, which is why it's our top pick.

No matter what your reason is for adding a probiotic to your dog’s diet, there is a pretty good chance that one of the thousands of happy pet owners using this product have overcome the same challenge. It’s as easy as opening a packet and sprinkling it over your dog’s food at mealtime. And your dog isn’t likely to complain about the taste; in fact, many people state that their dogs lick the bowl clean to get every last bit of this probiotic powder.

For about $30 you’ll get 30 packets of Purina Fortiflora, which is usually a month’s supply. This is a slightly above average price for a monthly supply of dog probiotics, but the track record of this product often justifies spending the extra few dollars. Some people stretch the box further by using half of a packet a day as maintenance—once their pup’s gut is back on track. 


CFU stands for Colony Forming Units, which is the number of alive and active microorganisms in one serving of a probiotic dietary supplement.

Best Budget: NUSENTIA Probiotic Miracle Supplement

NUSENTIA Probiotic Miracle Supplement

Courtesy of Amazon

If you’re shopping around for a budget-friendly pet probiotic, keep an eye on quality but skip individual packaging. Nusentia Probiotic Miracle Powder is our top pick for an affordable probiotic for dogs.

This powder formula is actually safe for use in both dogs and cats, which offers additional savings and convenience to multi-pet households. It’s also shelf-stable, so you don’t have to clear room in the fridge or worry about it spoiling in the pantry. There are six strains of probiotics in this formula, and each scoop will deliver about 1 billion CFU. This may not be as many CFU per dose as some other products, but the results indicate that this product is still highly effective.

Each container holds up to 360 servings, depending on the size of your pet. For dogs under 50 pounds (and cats), give one scoop. Dogs over 50 pounds get two scoops. This means that each jar of Nusentia Probiotic Miracle Powder will last anywhere from 6 months to a year, on average.

For less than $50 a year, your pet can experience relief from tummy troubles, gas, and other digestive distress. And while this may be a cheap probiotic powder for dogs, the product is made in the United States. The quality and quantity of Nusentia Probiotic Miracle Powder combine to make this a great choice for an affordable probiotic for pets.

Best Chew: PetVitalityPRO Probiotics for Dogs with Natural Digestive Enzymes

PetVitalityPRO Probiotics for Dogs with Natural Digestive Enzymes

Courtesy of Amazon

Many dog probiotics are available as a chew, which in your dog’s mind is practically the same as a treat! Give your dog healthy probiotics and a reason to wag his tail with the PetVitalityPro Probiotic Chew.

This duck-flavored soft chew has more than 20 active ingredients and includes a green superfood formula, so fair warning: it has a green-ish tint. A few pet parents said they were surprised by the color when they opened the container. Most dogs will gladly gobble this probiotic chew whole, but if for some reason your dog isn’t interested in an extra "treat," then these chews crumble easily and can be mixed in with a meal.

The best part about this probiotic chew for dogs is how fast it works for many pets. In cases of persistent itchiness or worrisome diarrhea, pet owners have noticed that their dogs experienced fast relief once they began a regiment that included PetVitalityPro Probiotic Chews. In fact, one pet parent pointed out that these worked more effectively than any other natural or medicinal approach she tried for her dog’s digestive distress. Turn treat time into an opportunity to give your dog a daily dose of good bacteria with these tasty PetVitalityPro Probiotic Chews for dogs.

Best for Digestion: Zesty Paws Probiotic Bites with Natural Digestive Enzymes Chews

Zesty Paws Probiotic Bites with Natural Digestive Enzymes Pumpkin Flavor Chews for Dogs

Courtesy of Chewy

If your dog is experiencing digestive distress or frequent tummy trouble, a probiotic with digestive enzymes may help to ease digestion and regulate elimination. Zesty Paws Probiotic Bites are a top choice and an all-natural supplement that works well for dogs large and small.

Each probiotic bite from Zesty Paws has six strains of probiotics and prebiotics and over 3 billion CFU, which is equivalent to some prescription-strength probiotics. This probiotic supplement for dogs adds pumpkin to support the overall function of the digestive tract and papaya to assist the stomach in breaking down fats and proteins. Together, these two additives make it easier for many dogs to properly digest and eliminate food.
Opinions are mixed on whether the taste is a winner. Some dogs gobble these chews up while others are more selective. In certain cases, pet parents had success getting even picky pets to eat the chew by crumbling it into their meal. In addition to assisting with digestion and elimination, this probiotic supplement has also helped many dogs that were lacking an appetite or had extreme lethargy.

Best for Older Dogs: Amazing Nutritionals Probiotic Joint Chewable Tablets

Amazing Nutritionals Probiotic Joint Chewable Tablets

Courtesy of Amazon

As your dog ages, new problems may begin to pop up. Tackle any developing digestive dilemmas and ease joint pain with a probiotic for senior dogs, like Amazing Nutritionals Probiotics Joint Formula.

This tablet has helped many older dogs that suffer from arthritis, joint pain, and stiffness. It omits many of the most common allergens for dogs, including wheat, corn, soy, egg, gluten and more but includes 7 billion CFU of beneficial bacteria. In addition, your dog will get a dose of MSM, chondroitin, and glucosamine to ease any arthritis and support joint and cartilage health.

People find that this supplement is a great choice for their senior dog and is an easy way to help them feel more comfortable and get around easier. Some dogs have been able to replace additional joint supplements with this single pill, but this varies for each dog. Either way, these probiotics for senior dogs are a great choice for supporting digestive health and mobility into the golden years and beyond.

Best for Puppies: Honest Kitchen Pro Bloom Instant Goat's Milk Probiotics

Honest Kitchen Pro Bloom Instant Goat's Milk Probiotics

Courtesy of Chewy

The puppy phase is a crucial stage of development, and as pet owners we want to give our dogs the best start in life that we can. Support a healthy gut from an early age by introducing an easy-to-digest probiotic for puppies, like Pro Bloom Instant Goat’s Milk & Probiotic Supplement from The Honest Kitchen.

Each serving contains an impressive 5 billion CFU of healthy bacteria. This beneficial bacteria can help your puppy improve digestion, ease elimination, strengthen the immune system, and also relieve an upset tummy due to diet changes or unsupervised snacking (since puppies have a tendency to get into things!).

People love how easy it is to give this supplement to their pups. Just add water to the human-grade instant goat’s milk and you have a ready-to-serve puppy probiotic treat. You can also pour the milk concentrate onto dry or dehydrated dog food before serving. While it isn’t mother’s milk, this probiotic for puppies is a healthy, nourishing way to support healthy growth and development. And even though it’s a great idea for helping puppies get the probiotics they need, it’s suitable for dogs of all ages.

Best for Allergies: Zesty Paws Allergy Immune Bites

Zesty Paws Allergy Immune Bites

Courtesy of Amazon

A surprising amount of allergy issues can be connected to gut imbalances, so it makes sense to help your pet have a healthy gut. The Allergy Immune Bites from Zesty Paws combine a robust blend of probiotics with a blend of supplements to promote both gut and immune health.

The Allergy Immune Bites contain both prebiotics and probiotics to help boost doggy digestion and support wellness through balanced gut bacteria. The blend contains both prebiotics and probiotics, and each chew contains 250 million CFU from five strains. This is not the most potent probiotic for dogs on our list and may not be a great choice if this is your only criteria in choosing a supplement. But if your pet also has allergy issues, then keep reading to see how this probiotic for allergies may help.

Specific ingredients to help your pet with allergy issues include EpiCor, a supplement blend of antioxidants, fiber, protein, and vitamins to help support the immune system. In addition, Omega-3 rich wild Alaskan salmon oil is blended into the formula to help remedy itchy skin. Pets with both food allergies and seasonal allergies have responded well by adding this probiotic and allergy support supplement to their diet. Some pet owners state that it took several weeks to notice a difference once they began giving this supplement to their dogs, but stick with it and you’ll have a healthier, happier, less itchy pet!

Best Spray: FloraZil+ Multi-Probiotic Food Spray For Dogs

FloraZil+ Multi-Probiotic Food Spray For Dogs

Courtesy of Amazon

If you’re looking for the simplest way to give your dog a daily dose of probiotics, a spray formula is hard to beat for convenience. The FloraZil+ Multi-Probiotic Food Spray is our choice for a probiotic spray that is easy to dispense while supplying beneficial bacteria for your pet.

This probiotic spray for dogs doesn’t need to be refrigerated, so store it in the place that is most convenient for you. Each milliliter of the liquid formula contains a minimum of 750,000 CFU of probiotics. The number of sprays in a single dose of the formula depends on the size of your dog, with smaller canines getting up to three sprays at a time and larger dogs getting anywhere from four to six sprays per meal.

Pet parents are quick to point out that this formula is commonly recommended by veterinarians, and that it’s easy to spray it on food before mealtime. Most pets seem to like the taste—and some wait for it before digging into their dinner. If measuring or mixing a supplement into your dog’s meal isn’t compatible with your daily routine, then FloraZil+ Probiotic Spray for dogs is a simple solution to support your dog’s gut while keeping things easy.

Final Verdict

Purina Fortiflora Canine Nutritional Supplement comes in pre-measured packets, making it easy to give your dog the correct daily dose of probiotics. PetVitalityPro Probiotic Chews are tasty duck-flavored soft chews that most dogs will happily gobble down.

What to Look for in Probiotics for Dogs

Ease of Use

Probiotics for dogs come in different formulations, including powders, capsules, tablets, chews and even sprays. Individual dogs may accept one formulation more readily, for instance, a powered that’s mixed into the food. Chewable products can also be convenient, though individual dogs might not like the taste of every chew. Some powered probiotics for dogs come in pre-measured doses, eliminating the need for measuring spoons. 

Species-Specific Probiotics

Always choose probiotics made specifically for dogs to ensure the product contains the correct strains of beneficial bacteria. Look for probiotic products that contain a guaranteed level of live microorganisms. 


Because probiotic products for dogs contain living organisms, they must be stored properly to keep the good bacteria alive. Follow all instructions on the product label. Some probiotics must be stored in the refrigerator, and all should be kept cool and dry, and away from overly warm temperatures. Always look at the use-by date on the package. After this time, the probiotics may no longer be effective.

  • Can you give a dog probiotics to help with diarrhea?

    Probiotics can be helpful for dogs suffering from diarrhea, especially diarrhea caused by stomach upset from switching foods abruptly, diarrhea caused by stress or anxiety, and diarrhea that occurs after using antibiotics. However, it’s important to see a veterinarian to find out what is causing your dog’s diarrhea as probiotics alone cannot always resolve diarrhea and your dog may need further tests or treatment. Always talk to your veterinarian before starting any supplement, including probiotics. 

  • Is yogurt a good probiotic for dogs?

    Small amounts of plain, unsweetened yogurt may provide dogs with some beneficial bacteria that might help improve digestion and gut health but there's no scientific evidence to back this up. Large amounts of dairy, including yogurt, can cause stomach upset in dogs, so give no more than 1 to 3 teaspoons of yogurt per day, depending on whether your dog is small, medium or large. 

Why Trust The Spruce Pets?

This article was written by Erica Puisis, a freelance writer who has contributed to The Spruce since 2017. To make this list, she considered each pick's recommended age, type, and use. Additional reporting was done by Jackie Brown, a writer, editor, and pet expert who has worked more than 25 years in the pet industry. 

Updated by
Jackie Brown
Jackie Brown
Jackie Brown is dog and cat breed expert. She's an award-winning writer with over two decades of veterinary medicine and pet publishing industry experience. Jackie has overseen many leading pet magazines, including <em>Dog World</em>, <em>Cats Magazine</em>, the award-winning <em>Rescue Proud</em>, and contributed to &#34;National Geographic’s Complete Guide to Pet Health.&#34;
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  1. Xu, Haiyan et al. Oral Administration of Compound Probiotics Improved Canine Feed Intake, Weight Gain, Immunity and Intestinal MicrobiotaFrontiers in immunology vol. 10 666. 2 Apr. 2019, doi:10.3389/fimmu.2019.00666

  2. Leaky Gut Syndrome in Dogs. VCA Hospitals.

  3. The Power of Probiotics. Cornell University College of Veterinary Medicine.

  4. Good Bugs/Bad Bugs – The Confusing World of Probiotic Supplements. Cummings Veterinary Medical Center at Tufts University.